What amounts did studies use?
Tesamorelin Dosage: What Did Each Study Give?
The amounts below come from studies, not a personal plan. Each one is paired with the people and time involved.
What do the study amounts mean for you?
This page lists study amounts so you can see what researchers tested, but it doesn't give a personal plan. Most large studies used 2 milligrams a day, given as one small shot under the belly skin.
A few smaller studies also tested 1 milligram. Most people in these studies had HIV.
The amounts tell what researchers gave those groups. They can't tell which dose is right for you.
Tesamorelin sold only for lab work isn't medicine approved for people. A study amount can't turn a lab product into a patient drug.
Which tesamorelin doses did the studies test?
Both main late-stage studies, called Phase 3 studies, used 2 milligrams under the skin each day [1][2]. The FDA-approved plan used the same daily amount.
The 26-week study included 412 people, and the follow-up was a 52-week study. The liver study and the 2024 study also used 2 milligrams a day [1][2][3][13].
A few smaller tests used a lower 1 mg/day shot. One involved older adults, while another involved people with diabetes.
A product's strength and its dose don't mean the same thing. The main proof still comes from studies using 2 milligrams.
Every amount here belongs to a named study group. It isn't a personal dosing direction for you.
How was tesamorelin given in the studies?
Every human study gave tesamorelin as a shot under the belly skin [1]. The FDA has approved only that way of giving it.
No useful pill, nose spray, or other form appears in the main studies. The stomach would break the medicine's short chain of protein parts down.
The approved drug is a dry powder that must be mixed before use. Its label gives the exact cold-storage rules and the deadline for the mixed medicine.
Those details can differ with the product in hand. They aren't steps for mixing or giving a shot at home.
Why did studies use one shot a day?
Tesamorelin leaves the blood fast. One lab calculation put its clearing rate at 1,060 liters per hour [1].
That figure is a math rate for falling drug levels. It doesn't mean that blood or body fluid left the person.
The medicine's level falls well before 1 hour. Yet the hormone change lasts after tesamorelin itself is gone [1].
One study found 13% more of the dose reached blood by day 14 than day 1 [1]. The study did not show whether that rise was helpful or harmful.
Age and similar traits didn't change the findings enough to matter. The study of how long tesamorelin stays gives the full account.
What changed at the main study dose?
At 2 milligrams a day, deep belly fat fell by 26 weeks. The drug group still had 18% less after 52 weeks [1][2].
The main test also tracked 1 growth protein made by the liver [1]. A review of five tests again found less deep belly fat [12].
A test in healthy men gave 2 milligrams a day and checked blood overnight. After two weeks, that 1 protein rose by 181 micrograms per liter, while blood sugar control stayed steady [4].
Most other volunteers had HIV and were watched by a medical team. These group results don't say what one person ought to take.
The doses belong to published studies. They aren't a plan for your own use.